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White Paper on cost implications of Leqembi and other anti-amyloid drugs for payers and ACOs and options for utilization management

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Introduction: The recent full approval of Lecanemab (Leqembi) by the FDA has ushered in a new era in the treatment of Alzheimer’s disease. As the first disease-modifying treatment to receive such approval, Leqembi offers hope to patients with early-stage Alzheimer’s. However, its adoption poses cost implications for payers and risk-bearing health systems. In a newly …

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Leqembi – Implications for Health Insurance Payers: A Comprehensive Analysis

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Introduction: On July 6, 2023, the FDA granted full approval to Lecanemab (Leqembi), marking a significant milestone as the first disease-modifying treatment for Alzheimer’s disease to receive such approval. This white paper aims to inform health insurance employees about the implications of Leqembi’s approval and offer insights into coverage considerations and potential cost implications. Coverage …

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FAQ About Leqembi

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About Leqembi Leqembi is the first of (very likely) many forthcoming drugs that will be revolutionizing the landscape of early stage Alzheimer’s disease. With its traditional (full) FDA approval come new questions from our patients and community surrounding its availability, manufacturer, purchasing options, working mechanism, insurance coverage, and comparisons with other medications. Our doctors here …

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President Carter and First Lady Rosalynn Carter dance at the annual Congressional Christmas Ball at the White House in 1978 in Washington, D.C. (Ira Schwarz / Associated Press)

Insights on former First Lady, Rosalynn Carter’s Diagnosis

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Rosalynn Carter, the former First Lady and a prominent advocate for mental health care, has been diagnosed with dementia, as announced by the Carter Center and reported by the New York Times. This revelation follows her husband, former President Jimmy Carter’s decision to enter hospice care. Despite the diagnosis, Mrs. Carter, at 95 years old, …

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Select evidence for the prevention of Alzheimer’s Disease

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FINGER study on Alzheimer prevention suggesting a multidomain intervention is effective in preventing a significant proportion of Alzheimer cases: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60461-5/fulltext Global study based on the FINGER study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222931/ CAIDE study on addressable Alzheimer Risk Factors: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(06)70537-3/fulltext Helpful overview of all risk factors and prevention recommendations: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244657/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514088/ The approach of the Weill Cornel Alzheimer prevention …

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Resources for caregivers

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Alzheimers.gov has put together a series of websites to help caregivers navigate the journey of caring for the loved ones: National Institute on Aging (NIA)Advance Care Planning Learn about financial and health care planning, including advance directives. National Institute on Aging (NIA)Alzheimer’s Caregiving Learn how to respond to changes in communication and behavior, provide everyday …

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Alzheimer’s Universe

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The Alzheimer’s Universe is a collection of resources put together by Weill Cornell Medicine on Alzheimer prevention:   AlzU.org was created by a team of experts to offer the most up-to-date information on Alzheimer’s disease (AD) prevention, treatment and caregiving. Join now to access one of 6 free online courses – one that focuses primarily on AD …

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